Theresa Delgadillo's work has been devoted to three areas: spirituality and religion, African Diaspora and Latinidad, and Latino/as in the Midwest. Her objects of study have included novels, autobiographies, memoirs, photographic collections, feature and documentary films, poetry and music. In research and teaching she explores the intersections among gender, sexuality, race and nation as well as critique these categories; engage with comparative, transnational and migratory paradigms and movements; pursue transdisciplinary knowledge; and desire to make socially transformative knowledge possible.
Future projects will focus on twentieth and twenty-first century comparative ethnic, multiethnic, postcolonial and women's texts in the Americas. She is interested in exploring topics such as spirituality, religion, nationalism, transnationalism, ethnicity, race, gender, sexuality, class, cultural and social change, history, memory, remembrance, diaspora, exile, identity, community, interpretation, networks, cross-cultural exchange, justice, intersectionality, hybridity, immigration and war in literature, visual culture and music.